Chaos Sanctuary a.k.a. Diablo Run (Act 4)In the event that they don't get something substantial or worthwhile during the River of Flame buy D2R ladder items, players can move on to second major area which is Diablo's stronghold in Chaos Sanctuary. Also, it has some of the most powerful and generous enemies within the game.
If the monsters don't drop anything eye-catching, then Diablo himself surely will. It's helpful that Diablo isn't too difficult an opponent to eliminate. Diablo's attacks are easy get rid of, and even a budget Bonemancer build can take on him.
The City Of The Damned (Act 4)The characters in the City of the Damned are among the easiest in the entire late game to destroy. They rely on elemental as well as poison immunity, so a Sorceress or Poison Nova Necromancer might wish to stay clear, but physical damage dealers can cut through the groups like butter.
If players are trying to achieve their highest level the game may become a slow slog. Try farming this area. There's no doubt that there are equipment and runes to collect that can help but the gain of experience in this area has no competitors.
Nilathak's Temple a.k.a. Pindle Run (Act 5)In Act 5 players don't need to travel far in Mount Arreat to get a ideal farming spot. The city of Harrogath already is one of the most frequently used grinding spots to be found in Diablo 2 Resurrected buy items. Nilathak's Temple is the place and players don't have to clear the entire zone clear.